Ask ten people with diabetes whether there's an insulin shortage in 2026, and you'll get ten different answers depending on which product they use and where they fill it. That's because "insulin" isn't one drug — it's a family of long-acting, rapid-acting, and premixed products made by three manufacturers, and 2026's supply problems are hitting different corners of that family for different reasons. This guide separates fact from headline: what's actually short, what's fine, why it happened, and what to do if you're the one standing at the counter with an empty prescription bottle.
1. Is There Really an Insulin Shortage in 2026?
Partially, and unevenly. The FDA's Drug Shortages Database and the ASHP/University of Utah Drug Shortage Resource Center — the two authoritative trackers pharmacists actually use — currently list several individual insulin products as being in shortage, including insulin aspart, insulin degludec, and insulin glargine-yfgn (the Semglee biosimilar). That's a real, documented supply problem. But it isn't a blanket shortage of "insulin" as a category — vials of Lantus, most forms of Humalog, Basaglar, Rezvoglar, and Toujeo are generally available at the national level, even while specific formats like Lantus SoloStar pens sit on intermittent back order.
The practical translation: whether you're affected depends almost entirely on which specific product, strength, and delivery device you use — not on "insulin" as a whole. A patient on Lantus vials may never notice a problem, while a neighbor on Lantus SoloStar pens gets turned away twice in one month.
2. Why This Is Happening: Four Overlapping Causes
Unlike a single-drug shortage caused by one factory issue, the 2026 insulin supply picture is the result of several separate decisions landing in the same window.
Cause 1: The Semglee discontinuation
Semglee (insulin glargine-yfgn), made by Biocon and marketed by Viatris, was the first FDA-approved interchangeable biosimilar to Lantus. Between 2022 and 2024 it captured significant market share as insurers steered patients toward the lower-cost option. Biocon began having its own supply problems with Semglee in mid-2025, and on December 31, 2025, discontinued it entirely. Every patient who had been filling Semglee needed a new insulin glargine source almost overnight — and that demand landed squarely on Lantus, Basaglar, and Rezvoglar, which is why Lantus SoloStar pens are now on intermittent back order.
Cause 2: Novo Nordisk's lineup streamline
Separately, Novo Nordisk discontinued its unbranded (authorized generic) insulin aspart and insulin degludec products, along with older NovoLog vial, FlexPen, and PenFill formats, effective December 31, 2025. The company paired this with list price cuts of up to 75% on remaining products starting January 1, 2026. The intent was to simplify the product line and lower list prices, but the near-term effect was fewer SKUs on the shelf while patients and pharmacies adjusted.
Cause 3: The Basaglar Tempo pen phase-out
Eli Lilly is separately discontinuing its Basaglar Tempo smart-pen platform. New Tempo pens are available only through July 27, 2026; the Tempo app stopped recording new dose data the following day, and the broader TempoSmart platform is scheduled to shut down entirely by the end of 2026. This doesn't affect standard Basaglar KwikPen supply, but it's a real transition Tempo users need to plan around.
Cause 4: GLP-1 demand pulling on the same manufacturing capacity
Novo Nordisk and Eli Lilly are the same companies making Ozempic, Wegovy, Mounjaro, and Zepbound — and demand for those drugs has grown faster than either company anticipated. Both companies have publicly stated that insulin production hasn't been deprioritized, but diabetes advocates have repeatedly raised concerns that manufacturing capacity, glass vials, and injection-device components are being pulled toward the more profitable GLP-1 category, indirectly straining insulin supply chains during periods of high demand.
3. Timeline: How We Got Here
| Date | Event |
|---|---|
| 2021 | FDA approves Semglee as the first interchangeable biosimilar to Lantus |
| 2022–2024 | Semglee and generic NovoLog/Tresiba gain significant formulary share as lower-cost options |
| 2023 | Sanofi announces a 78% Lantus list price cut and $35/month out-of-pocket cap, effective 2024 |
| Mid-2024 | Fiasp and Humalog begin showing regional manufacturing-related delays |
| Mid-2025 | Semglee begins experiencing its own supply constraints |
| Feb–Jul 2025 | FDA approves Merilog and Kirsty, two new insulin aspart biosimilars |
| Dec 31, 2025 | Semglee, unbranded insulin aspart/degludec, and older NovoLog formats all discontinued the same day |
| Jan 2026 | Novo Nordisk cuts list prices up to 75% on remaining insulin products |
| Jan–Mar 2026 | Demand shifts sharply to Lantus, Basaglar, Rezvoglar, NovoLog FlexTouch, and Humalog; insurers update formularies |
| Jul 27, 2026 | Last day Basaglar Tempo pens are distributed; standard Basaglar KwikPens unaffected |
| Aug 2026 | Sanofi confirms intermittent Lantus SoloStar pen supply; several products remain on the ASHP shortage list |
4. Current Availability by Insulin Type
| Product | Manufacturer | Status |
|---|---|---|
| Lantus vials | Sanofi | Generally available |
| Lantus SoloStar pens | Sanofi | Intermittent back order |
| Toujeo / Toujeo Max | Sanofi | Available |
| Basaglar KwikPen | Eli Lilly | Available |
| Basaglar Tempo pen | Eli Lilly | Being discontinued; new pens available only through 7/27/26 |
| Rezvoglar | Eli Lilly | Available |
| Semglee (insulin glargine-yfgn) | Biocon | Discontinued as of 12/31/25 |
| Tresiba U-100 | Novo Nordisk | Intermittent; generally better availability than U-200 |
| Tresiba U-200 | Novo Nordisk | Intermittent back order |
| NovoLog vial / FlexPen / PenFill | Novo Nordisk | Discontinued as of 12/31/25 |
| NovoLog FlexTouch pen | Novo Nordisk | Available; intermittent regional stockouts |
| Fiasp (vial & FlexTouch) | Novo Nordisk | Available; some regional shortages |
| Humalog vials (10 mL) | Eli Lilly | Available; supply largely stabilized |
| Humalog 3 mL vials | Eli Lilly | Discontinued (freed capacity for 10 mL vials) |
| Admelog | Sanofi | Available |
| Lyumjev | Eli Lilly | Available |
| Apidra | Sanofi | No current shortage; widely available |
| Kirsty (insulin aspart-xjhz) | Biocon/Viatris | Interchangeable biosimilar to NovoLog; availability expanding |
| Merilog (insulin aspart-szjj) | Sanofi | Biosimilar to NovoLog (not interchangeable); availability expanding |
Availability shifts week to week and varies by region and pharmacy chain. This table reflects national manufacturer and ASHP shortage-list status as of early August 2026 — always confirm with your specific pharmacy before assuming a product is in or out of stock.
5. Alternatives: What's Actually in Stock
If your usual insulin isn't available, here's how the substitutes line up by category. None of these are automatic pharmacy substitutions the way an interchangeable biosimilar is — most need a new prescription or at least a phone call to your prescriber's office.
| If you use... | Consider... | Key consideration |
|---|---|---|
| Lantus SoloStar pen | Lantus vials, Basaglar, Rezvoglar, or Toujeo | Toujeo is 300 units/mL — not a 1:1 unit swap |
| NovoLog vial/FlexPen | NovoLog FlexTouch, Humalog, Kirsty, or Merilog | Kirsty can be substituted by a pharmacist in most states; Merilog needs a new script |
| Tresiba U-200 | Tresiba U-100, Lantus, or Basaglar | U-100 and U-200 differ in concentration, not just volume |
| Semglee | Lantus, Basaglar, or Rezvoglar | Semglee is gone for good; pick a new long-term product with your prescriber |
| Basaglar Tempo pen | Standard Basaglar KwikPen | Same insulin, just without the connected-app features |
For deeper cost comparisons across brands, see our insulin price comparison by brand and pharmacy, and if cost — not just availability — is the real obstacle, our complete guide to free and $35 insulin walks through every current program in one place.
6. Pros & Cons of Switching Insulin Products
Reasons switching can work well
- Basaglar and Rezvoglar use the same 100 units/mL concentration as Lantus, so many patients use the same unit dose
- Interchangeable biosimilars like Kirsty can be substituted without waiting on a new prescription
- Newer products sometimes carry lower list prices post-2026 pricing cuts
- Switching proactively avoids an emergency gap in coverage
Reasons to be careful
- Toujeo's 300 units/mL concentration means the same "unit" count is a different physical volume than Lantus
- Insurance tier and copay can differ even between clinically similar products
- Non-interchangeable biosimilars (like Merilog) generally require a new written prescription, not a pharmacist swap
- Switching without medical guidance risks dosing errors, which can be dangerous with insulin specifically
7. Step-by-Step: What to Do If Your Pharmacy Is Out
Call ahead before your next fill
Call your pharmacy two or three days before you need a refill and ask specifically whether your product and strength are in stock, rather than finding out when you arrive with an empty pen.
Check nearby and independent pharmacies
Availability varies by chain and even by individual store. Independent pharmacies sometimes have stock that large chains don't, since they order from different distributors.
Contact your prescriber's office before you run out
Give your prescriber time to consider an alternative product rather than making the call at the pharmacy counter with no insulin in hand. Ask them to write the prescription using the generic name with permission to substitute where clinically appropriate.
Confirm insurance coverage for the alternative
Call your insurer or check your plan's current formulary before filling a substitute — coverage tiers have shifted repeatedly since the Semglee and NovoLog discontinuations. If your plan requires a prior authorization for the new product, see our prior authorization guide for how that process generally works.
Never ration or skip doses to stretch supply
If you're genuinely at risk of running out, contact your prescriber or pharmacist immediately. Reducing your insulin dose on your own to make a supply last longer carries serious health risks.
8. Eligibility Comparison: Programs That Can Help
Supply gaps often collide with cost concerns — if you're being pushed onto a new product anyway, it's worth knowing what assistance is available for it. Here's how the major insulin cost programs compare on who qualifies.
| Program | Who it's for | Insurance required? |
|---|---|---|
| Medicare $35 insulin cap (IRA) | Anyone enrolled in Medicare Part D or Part B | Yes — must be a Medicare enrollee |
| Medicare Extra Help (LIS) | Low-income Medicare Part D enrollees | Yes — must have Part D |
| Lilly Insulin Value Program | Insured or uninsured patients using Lilly insulins | No — works with or without insurance |
| Lilly Cares Foundation PAP | Uninsured/underinsured, income-qualified patients | No, but some Medicare Part D enrollees also qualify |
| NovoCare Patient Assistance Program | Uninsured/underinsured, income-qualified patients | No, generally must be uninsured |
| Novo Nordisk My$99Insulin | Any patient, any insurance status | No — open to everyone |
| State insulin copay caps (30+ states) | Patients on state-regulated commercial plans | Yes — plan must be state-regulated |
9. Income Limit Comparison
Income thresholds are published as a percentage of the Federal Poverty Level (FPL) and adjusted each year, so treat the dollar figures below as current 2026 approximations — always confirm the exact number for your household size at Medicare.gov or the program's own site before applying.
| Program | FPL threshold | Approx. annual income (1 person) |
|---|---|---|
| Medicare Extra Help (LIS) | 150% FPL | ~$23,500 |
| NovoCare PAP — insulin products | 400% FPL | ~$62,600 |
| NovoCare PAP — Ozempic specifically | 200% FPL | ~$31,300 |
| Lilly Cares — Group 1 (e.g., Trulicity) | 300% FPL | ~$47,900 |
| Lilly Cares — Group 2 (Humalog, Basaglar, Humulin) | 400% FPL | ~$63,800 |
| My$99Insulin / Lilly Insulin Value Program | No income test | Open to all |
Medicare beneficiaries specifically: Novo Nordisk requires Medicare enrollees with household income under roughly 150% of FPL to first show proof of an Extra Help denial before qualifying for the PAP. Lilly Cares allows some Part D enrollees into its Group 1 and Group 2 medications directly. Rules differ by manufacturer, so don't assume Medicare automatically disqualifies you — check the specific program.
10. Covered Medications by Program
| Program | Insulins covered |
|---|---|
| Lilly Insulin Value Program | Humalog, Basaglar, Lyumjev, and Lilly's authorized generic insulins |
| Lilly Cares Foundation PAP | Humalog, Basaglar, Humulin (Group 2, 400% FPL) |
| NovoCare PAP | NovoLog, Tresiba, and other Novo Nordisk insulins (400% FPL) |
| My$99Insulin | Most Novo Nordisk insulins, including NovoLog, Levemir, and Tresiba |
| Medicare $35 cap | Any insulin product on your Part D or Part B plan's formulary |
11. Application Process
Gather documents first
Most manufacturer PAPs need proof of income (tax return or pay stubs), proof of insurance status, and a completed prescriber section. Having everything ready before you start prevents back-and-forth delays.
Apply online or by phone
NovoCare applications go through NovoCare.com or 1-866-310-7549. Lilly Cares applications go through LillyCares.com or 1-800-545-6962. Both offer downloadable paper applications if you'd rather have your doctor's office fax it in directly.
Have your prescriber complete their section
Every PAP requires a signed prescriber portion confirming your diagnosis and prescription. This is usually the step that slows applications down the most — ask the office to prioritize it.
Submit and track status
You and your prescriber typically receive notification by mail, text, or fax once a decision is made. If approved, medication generally ships directly to your home or your prescriber's office — not through your regular retail pharmacy.
12. Approval Timelines
| Program | Typical timeline |
|---|---|
| My$99Insulin | Immediate at pharmacy counter — no application review |
| Lilly Insulin Value Program (savings card) | Immediate — present card at pharmacy |
| NovoCare PAP | Typically 2–4 weeks once all documents are received |
| Lilly Cares Foundation PAP | Typically 4–6 weeks; a 90-day supply usually ships once approved |
| Medicare Extra Help | SSA generally responds within about 30–60 days of application |
Don't wait until you're out to apply. Even the fastest income-verified programs take a few weeks. If you're facing a supply gap right now, the $35 savings cards and My$99Insulin work at the pharmacy counter today, while a longer-term PAP application is still processing.
13. Renewal Process
Patient assistance programs are not one-and-done. Most require annual re-enrollment, and none of them renew automatically:
- NovoCare PAP: Re-apply annually with updated income documentation; renewal reminders are typically sent 60–90 days before expiration.
- Lilly Cares Foundation: Enrollment generally covers a set period (commonly up to a year), after which you must reapply and requalify under the current FPL guidelines.
- Medicare Extra Help: The Social Security Administration reviews eligibility each year, usually using tax return data; a change in income or resources can trigger a reassessment mid-year.
- Savings cards (Lilly Insulin Value Program): These generally don't expire the same way — check your card's terms, since some require annual re-registration to keep the same card number active.
14. Common Mistakes to Avoid
- Waiting until the pharmacy says "no" to start looking for alternatives. By then you may have days, not weeks, of supply left.
- Assuming a PAP application that worked last year still applies. Income limits, covered medications, and manufacturer rules change — Novo Nordisk's Ozempic threshold dropped from 400% to 200% FPL as part of 2026 program changes, for example.
- Switching insulin concentration without adjusting the dose. Moving to Toujeo (300 units/mL) using your old Lantus (100 units/mL) unit count is a dosing error, not a substitution.
- Skipping the Medicaid denial letter step. Some uninsured-patient programs require proof of a Medicaid denial before they'll process your application — submitting without it just delays things.
- Not checking whether your product has an interchangeable biosimilar. Interchangeable products like Kirsty can be substituted at the pharmacy immediately, without waiting on your prescriber.
15. Decision Tree: What Should You Do Right Now?
If you're genuinely at risk of running out, don't wait — reach your care team the same day rather than rationing doses or going without.
16. Cost: What You Should Actually Pay
Regardless of the supply situation, no one should be paying list price for insulin in 2026 if they can help it. Medicare enrollees pay no more than $35 per month per covered insulin under the Inflation Reduction Act, with no deductible applied. Eli Lilly's savings card caps insulin at $35 a month for insured and uninsured patients alike, with no income verification required at the pharmacy counter. If you qualify for a Humalog savings card or want to compare pricing across pharmacies, see our insulin price comparison guide. For a full rundown of every free and low-cost insulin option, including how Novo Nordisk's patient assistance program and the Eli Lilly Patient Assistance Program work end to end, read our complete guide to free or $35 insulin in 2026.
If you're on Medicare and cost is the bigger issue than availability, it's worth checking whether recent Part D changes affect your specific plan, and whether you qualify for Extra Help — many eligible people never apply simply because they assume their income is too high.
