Updated August 9, 2026

Insulin Shortage 2026: Status, Causes & Alternatives

Evan Brown
Written by Evan Brown
Prescription Savings Researcher
Dr. Megan Harris, MD Medically Reviewed by Dr. Megan Harris, MD
Why trust this guide: This update draws on the FDA Drug Shortages Database, the ASHP/University of Utah Drug Shortage Resource Center, manufacturer statements from Sanofi, Eli Lilly, and Novo Nordisk, and current CMS guidance on the Medicare insulin cost cap — checked as of August 8, 2026. Refill Relay isn't paid by any manufacturer or pharmacy named in this guide.
Quick Answer

There's no single, official "insulin shortage" covering every product in 2026 — but several individual insulins are genuinely hard to find, and the reasons differ by product. Lantus SoloStar pens are on intermittent back order after Sanofi absorbed demand from the discontinued Semglee biosimilar. Tresiba, especially the U-200 strength, has been in and out of stock since 2024. And Novo Nordisk permanently discontinued the older NovoLog vial, FlexPen, and PenFill formats on December 31, 2025, shifting patients onto NovoLog FlexTouch pens or a rapid-acting alternative. Vials of Lantus, most Humalog presentations, Basaglar, Rezvoglar, and Toujeo remain broadly available. If your regular insulin is out of stock, alternatives exist, your out-of-pocket cost can usually stay at or below $35 a month, and this guide walks through exactly what to do next.

Key Takeaways

  • This isn't one shortage — it's three or four overlapping ones. Insulin aspart, insulin degludec, and insulin glargine-yfgn (Semglee) each carry their own ASHP shortage listing and their own cause.
  • Semglee's December 31, 2025 discontinuation is the biggest driver behind the current Lantus SoloStar pen squeeze, since millions of patients had to shift back to brand glargine products almost overnight.
  • Novo Nordisk discontinued older NovoLog and unbranded insulin formats at the end of 2025 as part of a lineup streamline, not a manufacturing failure — FlexTouch pens remain in production.
  • Two new interchangeable/biosimilar rapid-acting insulins — Kirsty and Merilog — are now approved and gradually easing pressure on NovoLog supply.
  • The $35/month Medicare insulin cap is still in effect for 2026 under the Inflation Reduction Act, with no deductible, on Part D and Part B.
  • Basaglar Tempo smart pens are being phased out — new pens are available only through July 27, 2026, though regular Basaglar KwikPens are unaffected.

Ask ten people with diabetes whether there's an insulin shortage in 2026, and you'll get ten different answers depending on which product they use and where they fill it. That's because "insulin" isn't one drug — it's a family of long-acting, rapid-acting, and premixed products made by three manufacturers, and 2026's supply problems are hitting different corners of that family for different reasons. This guide separates fact from headline: what's actually short, what's fine, why it happened, and what to do if you're the one standing at the counter with an empty prescription bottle.

1. Is There Really an Insulin Shortage in 2026?

Partially, and unevenly. The FDA's Drug Shortages Database and the ASHP/University of Utah Drug Shortage Resource Center — the two authoritative trackers pharmacists actually use — currently list several individual insulin products as being in shortage, including insulin aspart, insulin degludec, and insulin glargine-yfgn (the Semglee biosimilar). That's a real, documented supply problem. But it isn't a blanket shortage of "insulin" as a category — vials of Lantus, most forms of Humalog, Basaglar, Rezvoglar, and Toujeo are generally available at the national level, even while specific formats like Lantus SoloStar pens sit on intermittent back order.

The practical translation: whether you're affected depends almost entirely on which specific product, strength, and delivery device you use — not on "insulin" as a whole. A patient on Lantus vials may never notice a problem, while a neighbor on Lantus SoloStar pens gets turned away twice in one month.

2. Why This Is Happening: Four Overlapping Causes

Unlike a single-drug shortage caused by one factory issue, the 2026 insulin supply picture is the result of several separate decisions landing in the same window.

Cause 1: The Semglee discontinuation

Semglee (insulin glargine-yfgn), made by Biocon and marketed by Viatris, was the first FDA-approved interchangeable biosimilar to Lantus. Between 2022 and 2024 it captured significant market share as insurers steered patients toward the lower-cost option. Biocon began having its own supply problems with Semglee in mid-2025, and on December 31, 2025, discontinued it entirely. Every patient who had been filling Semglee needed a new insulin glargine source almost overnight — and that demand landed squarely on Lantus, Basaglar, and Rezvoglar, which is why Lantus SoloStar pens are now on intermittent back order.

Cause 2: Novo Nordisk's lineup streamline

Separately, Novo Nordisk discontinued its unbranded (authorized generic) insulin aspart and insulin degludec products, along with older NovoLog vial, FlexPen, and PenFill formats, effective December 31, 2025. The company paired this with list price cuts of up to 75% on remaining products starting January 1, 2026. The intent was to simplify the product line and lower list prices, but the near-term effect was fewer SKUs on the shelf while patients and pharmacies adjusted.

Cause 3: The Basaglar Tempo pen phase-out

Eli Lilly is separately discontinuing its Basaglar Tempo smart-pen platform. New Tempo pens are available only through July 27, 2026; the Tempo app stopped recording new dose data the following day, and the broader TempoSmart platform is scheduled to shut down entirely by the end of 2026. This doesn't affect standard Basaglar KwikPen supply, but it's a real transition Tempo users need to plan around.

Cause 4: GLP-1 demand pulling on the same manufacturing capacity

Novo Nordisk and Eli Lilly are the same companies making Ozempic, Wegovy, Mounjaro, and Zepbound — and demand for those drugs has grown faster than either company anticipated. Both companies have publicly stated that insulin production hasn't been deprioritized, but diabetes advocates have repeatedly raised concerns that manufacturing capacity, glass vials, and injection-device components are being pulled toward the more profitable GLP-1 category, indirectly straining insulin supply chains during periods of high demand.

3. Timeline: How We Got Here

The path to the 2026 insulin supply squeeze
DateEvent
2021FDA approves Semglee as the first interchangeable biosimilar to Lantus
2022–2024Semglee and generic NovoLog/Tresiba gain significant formulary share as lower-cost options
2023Sanofi announces a 78% Lantus list price cut and $35/month out-of-pocket cap, effective 2024
Mid-2024Fiasp and Humalog begin showing regional manufacturing-related delays
Mid-2025Semglee begins experiencing its own supply constraints
Feb–Jul 2025FDA approves Merilog and Kirsty, two new insulin aspart biosimilars
Dec 31, 2025Semglee, unbranded insulin aspart/degludec, and older NovoLog formats all discontinued the same day
Jan 2026Novo Nordisk cuts list prices up to 75% on remaining insulin products
Jan–Mar 2026Demand shifts sharply to Lantus, Basaglar, Rezvoglar, NovoLog FlexTouch, and Humalog; insurers update formularies
Jul 27, 2026Last day Basaglar Tempo pens are distributed; standard Basaglar KwikPens unaffected
Aug 2026Sanofi confirms intermittent Lantus SoloStar pen supply; several products remain on the ASHP shortage list

4. Current Availability by Insulin Type

Insulin product availability, current status as of August 2026
ProductManufacturerStatus
Lantus vialsSanofiGenerally available
Lantus SoloStar pensSanofiIntermittent back order
Toujeo / Toujeo MaxSanofiAvailable
Basaglar KwikPenEli LillyAvailable
Basaglar Tempo penEli LillyBeing discontinued; new pens available only through 7/27/26
RezvoglarEli LillyAvailable
Semglee (insulin glargine-yfgn)BioconDiscontinued as of 12/31/25
Tresiba U-100Novo NordiskIntermittent; generally better availability than U-200
Tresiba U-200Novo NordiskIntermittent back order
NovoLog vial / FlexPen / PenFillNovo NordiskDiscontinued as of 12/31/25
NovoLog FlexTouch penNovo NordiskAvailable; intermittent regional stockouts
Fiasp (vial & FlexTouch)Novo NordiskAvailable; some regional shortages
Humalog vials (10 mL)Eli LillyAvailable; supply largely stabilized
Humalog 3 mL vialsEli LillyDiscontinued (freed capacity for 10 mL vials)
AdmelogSanofiAvailable
LyumjevEli LillyAvailable
ApidraSanofiNo current shortage; widely available
Kirsty (insulin aspart-xjhz)Biocon/ViatrisInterchangeable biosimilar to NovoLog; availability expanding
Merilog (insulin aspart-szjj)SanofiBiosimilar to NovoLog (not interchangeable); availability expanding

Availability shifts week to week and varies by region and pharmacy chain. This table reflects national manufacturer and ASHP shortage-list status as of early August 2026 — always confirm with your specific pharmacy before assuming a product is in or out of stock.

5. Alternatives: What's Actually in Stock

If your usual insulin isn't available, here's how the substitutes line up by category. None of these are automatic pharmacy substitutions the way an interchangeable biosimilar is — most need a new prescription or at least a phone call to your prescriber's office.

Insulin alternatives by category
If you use...Consider...Key consideration
Lantus SoloStar penLantus vials, Basaglar, Rezvoglar, or ToujeoToujeo is 300 units/mL — not a 1:1 unit swap
NovoLog vial/FlexPenNovoLog FlexTouch, Humalog, Kirsty, or MerilogKirsty can be substituted by a pharmacist in most states; Merilog needs a new script
Tresiba U-200Tresiba U-100, Lantus, or BasaglarU-100 and U-200 differ in concentration, not just volume
SemgleeLantus, Basaglar, or RezvoglarSemglee is gone for good; pick a new long-term product with your prescriber
Basaglar Tempo penStandard Basaglar KwikPenSame insulin, just without the connected-app features

For deeper cost comparisons across brands, see our insulin price comparison by brand and pharmacy, and if cost — not just availability — is the real obstacle, our complete guide to free and $35 insulin walks through every current program in one place.

6. Pros & Cons of Switching Insulin Products

Reasons switching can work well

  • Basaglar and Rezvoglar use the same 100 units/mL concentration as Lantus, so many patients use the same unit dose
  • Interchangeable biosimilars like Kirsty can be substituted without waiting on a new prescription
  • Newer products sometimes carry lower list prices post-2026 pricing cuts
  • Switching proactively avoids an emergency gap in coverage

Reasons to be careful

  • Toujeo's 300 units/mL concentration means the same "unit" count is a different physical volume than Lantus
  • Insurance tier and copay can differ even between clinically similar products
  • Non-interchangeable biosimilars (like Merilog) generally require a new written prescription, not a pharmacist swap
  • Switching without medical guidance risks dosing errors, which can be dangerous with insulin specifically

7. Step-by-Step: What to Do If Your Pharmacy Is Out

1

Call ahead before your next fill

Call your pharmacy two or three days before you need a refill and ask specifically whether your product and strength are in stock, rather than finding out when you arrive with an empty pen.

2

Check nearby and independent pharmacies

Availability varies by chain and even by individual store. Independent pharmacies sometimes have stock that large chains don't, since they order from different distributors.

3

Contact your prescriber's office before you run out

Give your prescriber time to consider an alternative product rather than making the call at the pharmacy counter with no insulin in hand. Ask them to write the prescription using the generic name with permission to substitute where clinically appropriate.

4

Confirm insurance coverage for the alternative

Call your insurer or check your plan's current formulary before filling a substitute — coverage tiers have shifted repeatedly since the Semglee and NovoLog discontinuations. If your plan requires a prior authorization for the new product, see our prior authorization guide for how that process generally works.

5

Never ration or skip doses to stretch supply

If you're genuinely at risk of running out, contact your prescriber or pharmacist immediately. Reducing your insulin dose on your own to make a supply last longer carries serious health risks.

8. Eligibility Comparison: Programs That Can Help

Supply gaps often collide with cost concerns — if you're being pushed onto a new product anyway, it's worth knowing what assistance is available for it. Here's how the major insulin cost programs compare on who qualifies.

Eligibility snapshot by program
ProgramWho it's forInsurance required?
Medicare $35 insulin cap (IRA)Anyone enrolled in Medicare Part D or Part BYes — must be a Medicare enrollee
Medicare Extra Help (LIS)Low-income Medicare Part D enrolleesYes — must have Part D
Lilly Insulin Value ProgramInsured or uninsured patients using Lilly insulinsNo — works with or without insurance
Lilly Cares Foundation PAPUninsured/underinsured, income-qualified patientsNo, but some Medicare Part D enrollees also qualify
NovoCare Patient Assistance ProgramUninsured/underinsured, income-qualified patientsNo, generally must be uninsured
Novo Nordisk My$99InsulinAny patient, any insurance statusNo — open to everyone
State insulin copay caps (30+ states)Patients on state-regulated commercial plansYes — plan must be state-regulated

9. Income Limit Comparison

Income thresholds are published as a percentage of the Federal Poverty Level (FPL) and adjusted each year, so treat the dollar figures below as current 2026 approximations — always confirm the exact number for your household size at Medicare.gov or the program's own site before applying.

2026 income limits, single-person household (approximate)
ProgramFPL thresholdApprox. annual income (1 person)
Medicare Extra Help (LIS)150% FPL~$23,500
NovoCare PAP — insulin products400% FPL~$62,600
NovoCare PAP — Ozempic specifically200% FPL~$31,300
Lilly Cares — Group 1 (e.g., Trulicity)300% FPL~$47,900
Lilly Cares — Group 2 (Humalog, Basaglar, Humulin)400% FPL~$63,800
My$99Insulin / Lilly Insulin Value ProgramNo income testOpen to all

Medicare beneficiaries specifically: Novo Nordisk requires Medicare enrollees with household income under roughly 150% of FPL to first show proof of an Extra Help denial before qualifying for the PAP. Lilly Cares allows some Part D enrollees into its Group 1 and Group 2 medications directly. Rules differ by manufacturer, so don't assume Medicare automatically disqualifies you — check the specific program.

10. Covered Medications by Program

Which insulins each program actually covers
ProgramInsulins covered
Lilly Insulin Value ProgramHumalog, Basaglar, Lyumjev, and Lilly's authorized generic insulins
Lilly Cares Foundation PAPHumalog, Basaglar, Humulin (Group 2, 400% FPL)
NovoCare PAPNovoLog, Tresiba, and other Novo Nordisk insulins (400% FPL)
My$99InsulinMost Novo Nordisk insulins, including NovoLog, Levemir, and Tresiba
Medicare $35 capAny insulin product on your Part D or Part B plan's formulary

11. Application Process

1

Gather documents first

Most manufacturer PAPs need proof of income (tax return or pay stubs), proof of insurance status, and a completed prescriber section. Having everything ready before you start prevents back-and-forth delays.

2

Apply online or by phone

NovoCare applications go through NovoCare.com or 1-866-310-7549. Lilly Cares applications go through LillyCares.com or 1-800-545-6962. Both offer downloadable paper applications if you'd rather have your doctor's office fax it in directly.

3

Have your prescriber complete their section

Every PAP requires a signed prescriber portion confirming your diagnosis and prescription. This is usually the step that slows applications down the most — ask the office to prioritize it.

4

Submit and track status

You and your prescriber typically receive notification by mail, text, or fax once a decision is made. If approved, medication generally ships directly to your home or your prescriber's office — not through your regular retail pharmacy.

12. Approval Timelines

How long approval typically takes
ProgramTypical timeline
My$99InsulinImmediate at pharmacy counter — no application review
Lilly Insulin Value Program (savings card)Immediate — present card at pharmacy
NovoCare PAPTypically 2–4 weeks once all documents are received
Lilly Cares Foundation PAPTypically 4–6 weeks; a 90-day supply usually ships once approved
Medicare Extra HelpSSA generally responds within about 30–60 days of application

Don't wait until you're out to apply. Even the fastest income-verified programs take a few weeks. If you're facing a supply gap right now, the $35 savings cards and My$99Insulin work at the pharmacy counter today, while a longer-term PAP application is still processing.

13. Renewal Process

Patient assistance programs are not one-and-done. Most require annual re-enrollment, and none of them renew automatically:

  • NovoCare PAP: Re-apply annually with updated income documentation; renewal reminders are typically sent 60–90 days before expiration.
  • Lilly Cares Foundation: Enrollment generally covers a set period (commonly up to a year), after which you must reapply and requalify under the current FPL guidelines.
  • Medicare Extra Help: The Social Security Administration reviews eligibility each year, usually using tax return data; a change in income or resources can trigger a reassessment mid-year.
  • Savings cards (Lilly Insulin Value Program): These generally don't expire the same way — check your card's terms, since some require annual re-registration to keep the same card number active.

14. Common Mistakes to Avoid

  • Waiting until the pharmacy says "no" to start looking for alternatives. By then you may have days, not weeks, of supply left.
  • Assuming a PAP application that worked last year still applies. Income limits, covered medications, and manufacturer rules change — Novo Nordisk's Ozempic threshold dropped from 400% to 200% FPL as part of 2026 program changes, for example.
  • Switching insulin concentration without adjusting the dose. Moving to Toujeo (300 units/mL) using your old Lantus (100 units/mL) unit count is a dosing error, not a substitution.
  • Skipping the Medicaid denial letter step. Some uninsured-patient programs require proof of a Medicaid denial before they'll process your application — submitting without it just delays things.
  • Not checking whether your product has an interchangeable biosimilar. Interchangeable products like Kirsty can be substituted at the pharmacy immediately, without waiting on your prescriber.

15. Decision Tree: What Should You Do Right Now?

Is your pharmacy currently out of your usual insulin?
No, still in stock — fill as normal; no action needed right now.
Yes — continue below.
Do you have enough supply for a few more days?
Yes — check nearby pharmacies and call your prescriber's office to discuss an alternative calmly.
No, running low — continue below.
Is cost also a barrier, separate from availability?
Yes — ask about a $35 savings card or My$99Insulin today, and start a PAP application for the longer term.
No, just availability — focus on finding stock or an alternative product.
Result: Contact your prescriber or pharmacist immediately

If you're genuinely at risk of running out, don't wait — reach your care team the same day rather than rationing doses or going without.

16. Cost: What You Should Actually Pay

$35
Max monthly cost per insulin, Medicare Part D/B (IRA cap)
$99
90-day supply of most Novo Nordisk insulins via My$99Insulin, any insurance status
30+
States with their own insulin copay caps for state-regulated commercial plans

Regardless of the supply situation, no one should be paying list price for insulin in 2026 if they can help it. Medicare enrollees pay no more than $35 per month per covered insulin under the Inflation Reduction Act, with no deductible applied. Eli Lilly's savings card caps insulin at $35 a month for insured and uninsured patients alike, with no income verification required at the pharmacy counter. If you qualify for a Humalog savings card or want to compare pricing across pharmacies, see our insulin price comparison guide. For a full rundown of every free and low-cost insulin option, including how Novo Nordisk's patient assistance program and the Eli Lilly Patient Assistance Program work end to end, read our complete guide to free or $35 insulin in 2026.

If you're on Medicare and cost is the bigger issue than availability, it's worth checking whether recent Part D changes affect your specific plan, and whether you qualify for Extra Help — many eligible people never apply simply because they assume their income is too high.

Frequently Asked Questions

Not as one single nationwide event. Several individual insulin products — including insulin aspart, insulin degludec, and insulin glargine-yfgn — are listed on ASHP's national drug shortage database, and pharmacies nationwide report intermittent gaps. But it isn't a single across-the-board shortage; availability varies by product, formulation, and pharmacy.

Lantus SoloStar pens, Tresiba (especially the U-200 concentration), and older NovoLog delivery forms (vials, FlexPen, PenFill) are the most consistently reported gaps. NovoLog vials and FlexPen/PenFill cartridges were discontinued by Novo Nordisk at the end of 2025; NovoLog FlexTouch pens remain in production but with intermittent regional stockouts.

It's a combination of factors rather than one cause: Biocon discontinued the Semglee biosimilar on December 31, 2025, pushing millions of patients back onto brand Lantus and other glargine products; Novo Nordisk discontinued several older NovoLog and Tresiba delivery forms the same day to streamline its lineup; and manufacturers have been shifting production capacity toward high-demand GLP-1 medications.

Humalog (insulin lispro), Admelog, Lyumjev, and Apidra (insulin glulisine) are all clinically appropriate rapid-acting alternatives, and Kirsty (insulin aspart-xjhz) is an interchangeable biosimilar to NovoLog that a pharmacist can substitute without a new prescription in most states. Any switch should still be confirmed with your prescriber, especially if your dosing has ever been adjusted.

Usually, but not automatically. Formularies have been updated repeatedly since late 2025 to add alternatives as preferred products, but tier placement and prior authorization rules still vary by plan. Call your insurer or check your plan's current formulary before assuming a substitute will be covered at the same cost.

Medicare Part D and Part B enrollees pay no more than $35 per month per covered insulin product under the Inflation Reduction Act, with no deductible. Eli Lilly's savings card also caps insulin at $35 a month for insured and uninsured patients, and Novo Nordisk's My$99Insulin program lets any patient buy a 90-day supply of most Novo Nordisk insulins for $99, regardless of insurance status.

Sometimes. Novo Nordisk's Patient Assistance Program generally requires Medicare beneficiaries with income below 150% of the federal poverty level to first show proof they were denied Extra Help. Lilly Cares allows some Medicare Part D enrollees to qualify for its Group 1 and Group 2 medications, which include several insulins. Rules differ by manufacturer, so check the specific program before assuming you're excluded.

Eli Lilly is discontinuing the Basaglar Tempo smart pen platform. New Tempo pens are available through July 27, 2026, and existing pens can be used until they expire, but the Tempo app stopped logging new dose data on July 28, 2026 and the TempoSmart app and Tempo Insights portal are scheduled to shut down entirely on December 31, 2026. Regular Basaglar KwikPens are not affected and remain available.

Switching between same-concentration products like Basaglar and Rezvoglar is often straightforward under medical guidance, but you should never do it without confirming with your prescriber first — especially with Toujeo, which is three times more concentrated than Lantus and is not a 1:1 unit swap. Insulin dosing errors carry serious health risks, so always confirm a switch before filling it.

Other Drug Shortages in 2026

Disclaimer: This guide is for general educational purposes and reflects publicly reported insulin supply and assistance-program information as of August 8, 2026. It does not constitute medical advice. Supply conditions, income limits, and program rules can change quickly — confirm current availability with your specific pharmacy and current eligibility figures with the program directly before applying, and never change your insulin product, dose, or schedule without first talking to your prescriber. If you are unable to obtain your insulin and are at risk of running out, contact your prescriber's office or pharmacist immediately.

Evan Brown
About the Author
Evan Brown — Medical Content Researcher

Evan Brown is a medical content researcher who specializes in translating confusing prescription pricing and supply mechanics into practical guidance patients can actually use before they pay — or before they're turned away at the counter.

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Dr. Megan Harris, MD
Medical Review
Dr. Megan Harris, MD

Dr. Megan Harris, MD reviews health content for accuracy, checking supply status, dosing guidance, and pricing program details against current sources.

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